The Original Nano-Hydroxyapatite Toothpaste
Japanese Innovation. Global Standard.
Welcome to Apagard, the originator of modern remineralizing toothpaste. Developed in Japan by Sangi Co. and based on NASA technology, Apagard introduced the dental world to Nano-Hydroxyapatite (n-Ha), the revolutionary mineral that is clinically proven to restore and strengthen enamel.
For decades, Apagard has set the global standard for advanced, fluoride-free protection, trusted by those who demand scientific performance and exceptional quality.
Why Premio Is The Pioneer
Apagard Premio uses proprietary technology to deliver the most effective form of enamel restoration, making it the choice for discerning dental consumers worldwide.
- 🔬 Patented Nano-Hydroxyapatite (mHAP): Apagard’s proprietary form of Nano-Hydroxyapatite, known as mHAP (medical Hydroxyapatite), is a highly effective, biomimetic mineral identical to the compound making up 97% of your enamel. These nano-sized particles penetrate deeply into micro-fissures and defects, actively:
- Remineralizing Enamel
- Smoothing the Tooth Surface
- Reducing Hypersensitivity
- Adsorbing and Removing Plaque
- 🥇 Clinically Proven Results: Backed by decades of research and development in Japanese dental science, Premio has been providing powerful anti-cavity benefits and exceptional tooth restoration since 1980.
- ✨ Best Whitening Toothpaste 2026: By repairing microscopic surface imperfections, Apagard helps restore the natural translucency and luster of the enamel, leading to a visibly brighter, smoother, and healthier-looking smile.
- 🚫 Fluoride-Free Formulation: Enjoy powerful, professional-level protection without the use of fluoride, making it a safe and effective choice for all ages.
Shop the APAGARD Premio Advanced Oral Care Range
Explore the full line of Apagard products, each designed with superior mHAP technology for specific needs.
Our Promise: Restorative Science
“Apagard Premio is the original n-Ha toothpaste, bringing Japanese precision and decades of scientific proof to your daily routine. Experience the proven power of mHAP.”
Ready for science-backed enamel restoration? Explore the Apagard collection today!
Frequently Asked Questions (FAQs)
1. What is Apagard Premio toothpaste?
Apagard Premio is a premium Japanese remineralizing toothpaste formulated with Nano-Hydroxyapatite (n-Ha), the same enamel-building mineral used in NASA research. It is designed to strengthen enamel, repair micro-damage, reduce sensitivity, and deliver a naturally brighter smile without harsh abrasives.
2. How does Nano-Hydroxyapatite in Apagard Premio work?
Nano-Hydroxyapatite binds to weakened areas of tooth enamel, filling microscopic cracks and smoothing the surface. This remineralization process helps restore enamel integrity, reduce sensitivity, and improve overall tooth strength in a way similar to natural mineral deposition.
3. Is Premio effective for sensitive teeth?
Yes. Apagard Premio is widely recommended for tooth sensitivity because nano-hydroxyapatite seals exposed dentinal tubules and rebuilds enamel. Many users experience relief from sensitivity after consistent use.
4. Is Premio safe for daily use?
Apagard Premio is safe for daily brushing. Its formula is fluoride-free, SLS-free, and gentle on enamel, making it suitable for long-term use and for people looking for a clean, science-backed oral-care product.
5. Does Premio whiten teeth?
Apagard Premio provides a natural whitening effect by smoothing and restoring enamel, reducing surface stains, and enhancing light reflection. It does not use harsh bleaching agents, making it ideal for gentle brightening.
6. Is Premio fluoride-free?
Yes. Apagard Premio is 100% fluoride-free. The remineralizing benefits come from nano-hydroxyapatite, an enamel-identical mineral that strengthens teeth without relying on fluoride.
7. Can children use Apagard Premio?
Apagard Premio is generally safe for children, but parents often choose a children-specific nano-hydroxyapatite toothpaste for kids. Always consult a dentist for age-appropriate recommendations.
8. How is Premio different from regular toothpaste?
Most toothpastes clean the surface only. Apagard Premio not only cleans but also repairs enamel at the microscopic level, reduces sensitivity, provides natural whitening, and uses advanced Japanese nano-technology rather than standard fluoride-based remineralization.
9. How long does it take to see results with Premio?
Most users notice smoother teeth and reduced sensitivity within 1–2 weeks. Whitening and enamel-strengthening effects continue to improve with consistent daily brushing.
10. Is Premio recommended by dentists?
Apagard is widely recognized by dental professionals in Japan and globally for pioneering nano-hydroxyapatite technology. Dentists often recommend it for enamel repair, sensitivity relief, and safe daily whitening.
11. Does Premio contain SLS or harsh foaming agents?
No. Apagard Premio is free from Sodium Lauryl Sulfate (SLS) and other harsh surfactants, making it suitable for people with sensitive gums or mouth ulcers.
12. Where can I buy Apagard Premio online?
You can purchase authentic Apagard Premio from hydropaste.com, an online store specializing in nano-hydroxyapatite toothpastes and remineralizing oral-care products.
People Also Ask (PAA)
Is Premio good for enamel repair?
Apagard Premio is known for effective enamel repair because its Nano-Hydroxyapatite particles bond to weakened enamel, filling micro-cracks and restoring tooth structure. This helps strengthen teeth and reduce sensitivity.
Does Premio work better than fluoride toothpaste?
Apagard Premio uses Nano-Hydroxyapatite instead of fluoride. While fluoride strengthens the outer layer, nano-hydroxyapatite rebuilds enamel directly by replacing lost mineral content. Many people choose it as a fluoride-free alternative for deeper remineralization.
Is Premio safe to use every day?
Daily use is safe. The formula is gentle, non-abrasive, and free from fluoride and SLS. It supports long-term enamel maintenance and oral health.
Does Premio whiten teeth naturally?
It whitens teeth by smoothing the enamel surface and reducing stain buildup. The whitening effect comes from remineralization rather than bleaching, which makes it suitable for people with sensitivity.
Is Premio good for cavities?
Nano-Hydroxyapatite helps remineralize areas of early-stage decay and strengthens enamel, making teeth more resistant to future cavities. It is often recommended for people prone to enamel erosion.
What makes Apagard Premio different from other Japanese toothpastes?
Apagard Premio stands out because it was developed by Sangi Co., the pioneer of nano-hydroxyapatite technology. It offers higher n-Ha concentration than basic Apagard variants for more intensive enamel repair.
Can I use Apagard Premio if I have sensitive teeth?
Yes. Apagard Premio seals exposed dentinal tubules, which reduces pain from cold, heat, and sweets. It is widely used as a sensitivity toothpaste.
Is Apagard Premio suitable for whitening after braces?
It works well after orthodontic treatment because it rebuilds enamel and smooths white spot lesions, which can appear after braces.
Does Apagard Premio contain any harsh chemicals?
No. It is free from fluoride, SLS, parabens, and strong abrasives. The formula is designed to be gentle on enamel and gums.
How long should I use Apagard Premio to see results?
Most people see smoother, shinier enamel and reduced sensitivity within 1–2 weeks of regular brushing.